| Worm gene name: | ver-4 |
| Worm sequence name: | F59F3.5 |
| Related human gene: | VEGF |
| Associated human disease: | susceptibility to atherosclerosis |
| People involved in this project: |
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| Left primer sequence: | tgaagccaaattcgacagtg |
| Right primer sequence: | gcttctgttcctccaagtgc |
| Size of PCR product: | 524 |
| Brief description: | In humans, VEGF is a protein crucial to endothelial cell growth. When mutated, endothelial cells do not replicate sufficiently to keep blood vessels supple. Suppressing VEGF in tumor masses is useful for shrinking tumors by limiting formation of new blood vessels. In worms, a mutation in ver-4 results in the following phenotypes: sluggish, slow growth, and abnormal protein aggregation. |
| Report any problems that might have appeared and any solutions: | |
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